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AN YOU IDENTIFY FIBROMUSCULAR DYSPLASIA
OF INTERNAL CAROTID ARTERIES?

 

Fibromuscular Dysplasia  (FMD) is noted to be the second most common cause of angiographically demonstrated narrowing of an artery, while arteriosclerosis is the most common cause, as stated in Fibromuscular Dysplasia of Internal Carotid Arteries with Doppler ultrasonic studies in the New York State Journal of Medicine/February 1983 by Reinhold E. Schlagenhauff, M.D.; Abdulmajeed Khatri, M.D., the Department of Neurology, Erie County Medical Center, and the State University of New York at Buffalo. 

“FMD is a proliferation of the media by hyperplasia of the muscular and fibrous tissue. The diagnosis of FMD depends on the characteristic angiographic appearance of “beaded” or “corkscrew” vessels.  Definitive diagnosis of FMD is usually made on the basis of carotid arteriography, which was found to affect the middle 2 to 3 cm of the cervical portion of the artery.  The typical “string of beads” appearance invariably produces narrowing of the lumen”. 

Below are some examples of the typical beaded appearance as well as velocity increases caused by FMD of the internal carotid artery. Click each image below for a full screen image and additional information.


Distal ICA color flow FMD

Distal ICA "beaded"

Distal ICA Velocity increase w/"string of Beads"

Distal ICA Velocity Increase FMD
 
Distal ICA Velocity increase w/"Corkscrew"
more info

 

PLAQUE CHARACTERIZATION AND COMPOSITION

 What is plaque character and composition?  Plaque is either hypoechoic or hyperechoic, homogenous or heterogenous in character.  For anatomic plaque evaluation the criteria of several authors provide a subjective diagnosis of plaque characteristics. There are different ways in which to categorize plaque. Plaque is considered homogenous if all of the echoes are of the same amplitude (hypoechoic or hyperechoic).  There have been no documented cases of a hyperechoic lesion that appeared completely homogeneous.

The plaque is heterogeneous if echoes are of unequal amplitudes (hypoechoic and hyperechoic).  This type of lesion may be in the pre- complex stage of development.  Plaque is characterized as complex when calcified formations involve the luminal arterial walls or the plaque itself.  If any concave areas or craters measure at least 1mm by 2mm, they are considered complex and are suspicious of ulceration. If an anechoic area is present it must be considered complex also.

Anechoic areas appear as an echolucent space between the intima and the plaque surfaces.  The longitudinal view should produce echogenic connections at the proximal and distal ends.  If the proximal, distal, or both ends ail to have a complete echogenic connection to an adjacent structure it is labeled “lipping”.

 

When plaque has both proximal and distal lipping, the presence of ulceration is highly probable, even if no crater or concaved area is present.  This phenomenon has been reported in the literature in 1-15% stenosis and the 16-49% stenosis WHICH IS IMPORTANT, IF THE PATIENT IS SYMPTOMATIC.

Here are some examples of complex plaque with ulceration, proximal and distal lipping.

Crater, Calcific, and Lipping

Color flow w/stenosis and spectrum

Ulcerations, proximal and distal lipping

   
 



 
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